new YORK (Reuters Health) – infection with the virus of
human immunodeficiency ( HIV) increases 70 percent the
risk for developing lung cancer regardless of the
smoking, according to the largest study reveals up
now on this Association.
“even after considering the smoking and the risk factors
“
traditional lung cancer, we find that there is a
independent mechanism associated with HIV increases the
“
risk of lung cancer in infected people“, said the
Dr. Keith Sigel, the Mount Sinai School of medicine in
New York, and author of the study.
People with HIV have high risk of developing
lung cancer, according to the team Sigel in the magazine
AIDS. But it is unknown if it is because they are more likely to smoke or
by a bias in the surveillance.
Then, the team crossed the Virtual cohort data of the
Cohort study on the aging of Veterans of the
Central Registry of Veterans Affairs.
A total of 37.294 people with HIV and 75.750 people
healthy, 1.071 developed lung cancer. The rate of cancer
per 100,000 persons per year was 204 in the cohort with
HIV and 119 in the control group.
After considering smoking, age, ethnicity, the
chronic obstructive pulmonary disease and previous pneumonias, the
reason for the incidence rate of HIV and lung cancer
remained significant (1.7).
There was no difference in the stadium at the time of diagnosis
among patients with HIV and the control group, which
suggests that monitoring bias did not influence the increase of
the rate of cancer in the group with HIV.
HIV infection could strengthen the risk of
develop lung cancer to suppress the immune system
and cause chronic inflammation, he said Sigel.
“the effect of smoking increases risk 70 by
“
%, so quitting is the main objective. “The
smoking cessation is key for patients with HIV”, indicated.
The author also considered that it will be important to determine if
the research of lung in people with HIV cancer brings
the same, more or less benefits than in persons without the
virus. And believed that another question to answer is whether the cancer
lung is more aggressive in people with HIV.
Source: AIDS, 29 February 2012 online
