Month: September 2011

50% Of Visual disorders in adults could have been prevented during childhood.

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50% Of the adult visual disorders could have been prevented for the childhood

-Bavarian clinic specialists recommend periodic reviews

-the lack of interest in reading and writing, the constant flashing and headaches may be symptoms of eye problems

-A bad vision of children impacts negatively on their school performance

Madrid, 2011-September amblyopia or lazy eyestrabismus and the problems of refractive errors like nearsightedness and astigmatism, hyperopia, are some of the most common ophthalmologic complications among children. So the vision to develop correctly, both eyes must function normally during childhood, because it is considered that visual maturity is reached approximately at the age of six. For this reason, Bavaria clinic specialists consider that 50% of ocular dysfunctions of adults could have been prevented during childhood.

“ An early diagnosis is essential to tackle such problems. It is very important that a specialist review in view of our children every two years. The ideal would be to conduct a comprehensive review at the time of the birth, a review six months and, subsequently, biannual explorations ”, said Dr. Fernando Llovet, Medical Director of Clínica Bavaria. “ That Yes, if at some point we suspect that your child has any visual difficulty must go to specialist immediately ”, recommends Dr. Llovet.

When a child turns his head or closing one eye when reading, he writes in twisted lines, does not show special interest in reading and writing because he is tired, was very close to the television, excess blinking or suffers from frequent headaches, there are signs that should alert parents and teachers. Solve these problems is very important because a bad view has a negative impact on the achievement of the child.

“ The smaller is the child, more complicated is detect a visual problem. It is important to monitor their eyes from birth, also during the first months and particularly when the child sees the TV or sits down to do games or work at a short distance ”, says specialist clinic Bavaria. “ Usually the child doesn’t notice that has a visual problem, because it is customary to see wrong. For this reason, we must be very attentive to any strange symptoms ”, concludes Dr. Llovet.

Clinic Bavaria

Clínica Baviera is a Spanish medical institution specializing in ophthalmology, with 60 centres, is present in several European countries (Spain, Germany, Austria, Holland, Italy). Founded more than 25 years ago, the quality of care, the permanent improvement of results and the incorporation of innovative and solvent techniques have been its raison d ’ être.

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Grünenthal Pharma launches Spain Palexia ® retard, a new generation of central action analgesics

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Grünenthal Pharma launches retard, a new generation of analgesics of central action in Spain Palexia ®

-Palexia ® retard is the representative of a new generation of analgesics of central action called MOR-NRI1, 2

– has shown broad efficacy in severe chronic pain, whether of origin nociceptivo or neuropático3-7

-sinérgico8 (MOR-NRI) and dual action mechanism provides an efficiency comparable to the of the classic powerful opioids such as oxycodonewith a lower incidence of reactions adverse that they lead to a lower rate of terminations of tratamientos3-6.

Madrid, September of 2011. Grünenthal Pharma, pharmaceutical company relating to the treatment against pain worldwide, launches in Spain tapentadol, already available in hospitals and in Spanish pharmacies under the name Palexia ® retard. Tapentadol retard is the first molecular entity developed for the treatment of severe chronic pain on the market since more than 25 años2, as well as representative of a new generation of so-called central action analgesics MOR-NRI1, 2 (the µ-opioid receptor agonist and norepinephrine reuptake inhibitor). The results of numerous studies show that Palexia ® retard is effective in nociceptivo pain and neuropathic pain, as demonstrated in models preclínicos9 and clinical studies on indications of severe chronic pain as lumbar pain crónico3, arthrosis of knee 4 or polyneuropathy diabética7.

Complementary mechanisms of action

Tapentadol combines in a single molecule a mechanism of dual and synergistic action and presents únicas2 pharmacokinetic characteristics, 8, 10. Both the agonismo µ-opioid (MOR), such as the inhibition of reuptake of norepinephrine (NRI), contribute complementary and sinérgica8 to the effectiveness of tapentadol in conditions of nociceptivo and neuropático9 pain. At the spinal level, tapentadol reduces transmission of painful signal via ascending through the activation of the µ-opioids recipient pre and post synaptic. In addition, tapentadol inhibits reuptake of norepinephrine (NA) in via downward, increasing levels of it in the synaptic cleft. This NA join α2 receptors, thus reducing the transmission of the dolor10. The combination of these two mechanisms of action in a single molecule can be advantageous in indications that often involve both components of pain, nociceptivo and neuropathic, as chronic low back pain intensa3.

This dual and synergistic action in the same molecule mechanism provides efficient both in pain nociceptivo as neuropathic, as well as a saving effect µ-opioid, giving rise to a smaller number of adverse effects usually associated with powerful opioid clásicos10.

Improving the control of pain

Pain is a serious health problem with more than six million Spaniards (17,25%), and if we speak of chronic pain, 20% of the population of Europe is affected by él11. Numerous studies have shown that pain has an impact very negatively on the quality of life of patients. In fact, more than half of people with severe pain (53%) recognize that they have been forced to reduce or limit their usual social activities. It is also closely linked to low labour productivity: 39,39% of people who suffer severe pain are absent from their jobs, compared with a 3.32% of the population not as padece12.

Currently, pharmacological treatment of severe chronic pain is typically inefficient due to the difficulty of maintaining the balance between adequate pain relief and an acceptable tolerability. This is what is known as the vicious circle, of which often is the interruption of treatment. Patients with chronic pain leave more frequently its treatment with opioids because of adverse effects that due to lack of eficacia13.

The best approach to pain needs to identify its mechanism and their symptoms and decide as well, the most appropriate for different types of dolor14 treatment, 15. The mechanisms of modulation Palexia ® MOR-NRI retard contributes to the analgesic effect and are complementarios1, 10.

Also, tapentadol has been included as a narcotic substance in Spain following the recent adoption of Royal Decree 1194 / 2011, which regulates the procedure by which a substance is considered narcotic.

About Grünenthal

Grünenthal is a pharmaceutical company concerning the treatment of pain worldwide, both for patients and for doctors and health managers. Innovation is one of its fundamental principles and one of the keys to be leaders in the global market for moderate to severe pain. Grünenthal is an independent German company family-owned, with offices in 36 countries around the world. Founded in 1946, Grünenthal has 347 employees in the region of Iberia and approximately 4,900 at the global level. In 2009 global sales figures reached 881 million euros. Also, Grünenthal Pharma ranked 17 in the Group of companies of between 250 and 500 employees in the prestigious ranking ‘ Best WorkPlaces 2011 Spain ’, produced by Great Place to Work ®

references

1. Kress HG. Tapentadol and its mechanism of action two: Is there a new pharmacological class of centrally acting analgesic on the horizon?. EUR J Pain 2010; 14 (8): 781-783.
2. Blasco, Berzosa M, Iranzo V, Camps C. Update in cancer pain. Cancer Chemother Rev 2009; 4 (2): 95-109
3. Buynak R Shapiro DY, Okamoto A., Van Hove I, Rauschkolb C, Steup to et to the. Efficacy and safety of tapentadol extended release for the management of chronic low back pain: Results of to prospective, randomized, double-blind, placebo-and active-controlled Phase 3 study. Expert Opin Pharmacother. 2010; 11 (11): 1787-1804.
4. Afilalo M Etropolski MS Kuperwasser B, Kelly K, Okamoto A., Van Hove I, et to the. Efficacy and safety of tapentadol extended release compared with oxycodone controlled release for the management of moderate to severe chronic pain related to osteoarthritis of the knee: Results of a randomized, double-blind, placebo-and active controlled Phase 3 study. Clin Drug Invest. 2010; 30 (8): 489-505.
5. Lange B, B Kuperwasser, Okamoto, Steup, Häufel T, Ashworth J et to the. Efficacy and safety of tapentadol prolonged release for chronic osteoarthritis pain and low back pain. ADV Ther. 2010; 27 (6): 381-399.
6. Wild JE, Grond S, B Kuperwasser, Gilbert J, McCann B, Lange B, et to the. Long-term safety and tolerability of tapentadol extended release for the management of chronic low back pain or osteoarthritis pain. Pain Pract. 2010; (10) 5: 416-427.
7. Schwartz S, Etropolski M, Shapiro DY, Okamoto A., Lange R, J. Haeussler, et to the. Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: Results of to randomized-withdrawal, placebo-controlled trial. Curr Med Res Opin. 2011; 27 (1): 151-162.
8. W. Schröder, Tzschentke TM, Terlinden R, De Vry J, U Jahnel, Christoph T, et to the. Synergistic interaction between the two mechanisms of action of tapentadol in analgesia. J aliment Exp Ther. 2011; 337 (1): 312-320.
9. W. Schröder, De Vry J, Tzschentke T, U Jahnel, Christoph T. Differential contribution of opiod and noradrenergic mechanism of tapentadol in rat models of nociceptive and neuropathic pain. EUR J Pain. 2010; 14 (8): 814-21.
10. Tzschentke T Jahnel U B Kögel, Christoph T, Englberger W, De Vry J et to the. Tapentadol hydrochloride: next generation, centrally acting analgesic with two mechanism of action in a single molecule. Drugs Today. 2009, 45 (7): 483-496.
11. Breivik H Collet B, Ventafridda V, Cohen R, Gallacher D. (2006). Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment. EUR J Pain. 2006; 10 (4): 287-333.
12. Langley PC… The prevalence, correlates and treatment of pain in Spain. J Med Econ. 2011; 14 (3): 367-380.
13. Varrasi G, Mmuller – Schwefe G, Pergolizzi J, Ornska A, B Morlion, Mavrocordatos P, et to the. Pharmacological tratment of chronic pain: the need for a CHANGE. Curr Med Res Opin. 2010; 26: 1231-45.
14. Woolf CJ, Mannion RJ. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet. 1999; 353: 1959-64
15. Woolf CJ, Max MB. Mechanism-based pain diagnosis, for analgesic drug development issues. Anaesthesiology. 2001; 95: 241-249

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Mint cigarette: easier to begin with, more difficult to leave

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Mint cigarette: easier to begin with, more difficult to leave

the pulmonologists recommended the exclusion of the menthol as an additive in cigarettes to avoid its harmful effects

-menthol increases the number of extra-thin particles in the smoke of tobacco with a higher risk for the health.

-smokers of menthol cigarettes are more addicts than not menthol smokers

– Softness and freshness of menthol cigarettes provide the home the habit.

Spain, 2011-September The prevention magazine of the smoking of the Spanish society for Pneumology and thoracic surgery has published an editorial prepared by a group of respiratory experts in smoking which, based on the review of the existing scientific literature, analyzes the characteristics of menthol cigarettes. The article concludes that far from the popular image driven by advertising for tobacco companies that menthol cigarettes was the “ least bad ” for health, the reality is that due to its characteristics it favors the home CHD habit, creates greater dependence and hinders the abandonment, so the pulmonologists demand the authorities to investigate the prohibition of the use of the menthol as an additive in cigarettes.

Menthol is a secondary alcohol found in the oils of peppermint. The main reason for mixing it with tobacco is using sensory effects of Mint to mask the negative effects of the roughness, hardness (irritability) tobacco smoke and superimpose their positive qualities. On the one hand, thanks to stimulate cold receptors, it gives the feeling of a fresh and deep breathing, and on the other hand, its local analgesic effect softens the effect of smoking. This is the reason why Mint smoking favors uptake and retention of young people and adolescents to tobacco.

A study of Hersey 2006 et to the showed that menthol cigarette consumption is significantly more common in middle school students and that adolescents who began to smoke were higher percentage with menthol cigarettes compared with non-menthol. “ Menthol is added in part because it is known that he has an attractive feature for inexperienced smokers or those who reject the roughness of the tobacco and menthol cigarettes more “ easy ” smoking ” explains to Dr. Sigismund Solano, Hospital General Universitario Gregorio Marañón pulmonologist and member of the SEPAR.

Another known effect of menthol is its ability to nicóticos recipients desensibilizadora is greater than the nicotine itself and the recovery of this desensitization is slower. The research carried out in recent years by teams of neurologists as Ahijevych K et to the. Je Muscat et to the. they establish not only are addicted to nicotine but also to the impact and perceptions of menthol smokers of menthol. “ An example is the time passed until the first cigarette in the morning of smokers with menthol is shorter than normal cigarettes smokers, which is indicative of greater addiction ” points Dr. Solano.

Perhaps because it increases the level of addiction, menthol cigarette smokers have low percentages of cessation and high relapse because the effect nicotine reward joined also the reward associated with menthol: freshness and softness. Dr Solano also emphasizes the study of Pletcher. It was the first to find significant number of relapses and the greatest difficulty increases to quit but also noted that the effects on health are very similar between menthol and not menthol cigarettes. “ This is important to note because he has often wanted to relate the cigarette Mint with the benefits associated with remedies medicinal with menthol as balsams, liniments or throat tablets, and presented to the cigarette Mint as a healthy and safe with no Mint cigarette alternative, but it is shown that this idea is completely false and smoking is harmful to health ” explains Dr. Solano.

“ After this study, concludes Dr. Solano seems demonstrated that menthol increases damage in smokers because it facilitates the initiation, reinforces the dependence and reduces the success of the processes of abandonment ”. Complex interactions with the addictive effects of nicotine has also been noted. For example, some evidence suggests that adding menthol power damage to increase the number of extra-thin particles in the tobacco smoke which implies higher risk of myocardial infarction. Therefore, the authors pose competent authorities should assess the exclusion of the menthol as an additive in cigarettes.

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Mutual Union obtained a surplus of 113 million

Mutual Union obtained a surplus of 113 million

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mutual Union obtained a surplus of 11 ’ 3 million

the mutual closes the accounts of 2010 positive

the management of the entity, based on the reduction and control of spending, allow a surplus 3 ’ 9 times higher than in 2009. Integration into mutual Corporation explains, in part, the good results economic.

Spain, 2011-September during the fiscal year 2010, Union of mutual revenue amounted to 224 ’ EUR 7 million. The difference between revenue and expenditure resulted in a positive outcome of 11 ’ €3 million, the number of protected workers reached the 251.660 and the number of mutual companies added 45.517. In addition, it provided 11 million to the Ministry of labour.

Planning, the implementation of austerity measures, saving and spending controls have enabled the successful economic, by multiplying by 3 ’ 9 the results of 2009, the year in which 2 were ’ 9 million positive.

the managing director, Juan Enrique Blasco has stressed that, despite continuing installed in the economic crisis, “ mutual Union is making a great effort to maintain a good cash surplus to continue offering the highest quality in the health care benefits, personalized attention, and the extension of the preventive culture entrepreneursworkers and self-employed ”.

Blasco underscored the ongoing work of the mutual help businesses increase productivity, improve the health of workers, and seeking practical solutions to labour welfare involving all levels of the company.

In this regard, stresses the positive downward trend in accidents in mutual companies, with a decline of 6 ’ 6% in 2010 compared to 2009. Also, in the past two years, period 2008 to 2010, workplace accidents dropped a 29 ’ 1%.

According to the managing director, becoming part of Corporation is one of the reasons why mutual Union is achieving positive results. “ The combined entity to facilitate the implementation of economies of scale, which generates significant savings in costs and streamlining the management of resources ”.

Currently, Muta Corporation has established itself as a reference management within mutualism, represents 24% of market share, with the industry’s largest network of centres, consisting of 330 own centres and 650 concluded.

With the creation of a unique network of centers, mutual eight share their facilities for the provision of health assistance, which has avoided that 210,000 assists have been covered with outside media.

He has also enabled Corporation since 2008 have made 450,000 assists and medical evidence exchanged, which resulted in an estimated annual savings of 2 ’ of EUR 5 million.

This online sharing facilities, means and facilities is underway in the integration of the systems of management, technology and information systems, taking a position pioneer in the sector.

The eight mutual to form part of one larger entity can also obtain competitive advantages in the field of innovation and research. And it is what makes possible mutual Corporation, along with the Pompeu Fabra University and Institute of Association of work, environment and health, ISTS, they have created the Center for research in occupational health, CISAL, which is currently becoming national focal point in international in the field of research relating to occupational health.

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The autonomous communities should be at the end of the 2010 nearly 690 million euros to private hospitals

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the autonomous communities should nearly 690 million euros to private hospitals at the end of the 2010

Madrid, September of 2011. The average period collection which had the private centres with the autonomous communities to 12 31, 2010 according to a study by the National Federation of clinics in 75 Spanish private hospitals was 160 days. In the same way the FNCP points out that this average collection period has worsened in 2011 in a substantial way.

Communities with a greater average of surveyed hospitals payment period were Extremadura with a 292 days of delay, with 271 days Madrid, Valencia, with 267 days and Castilla La Mancha with 263 days. On the other hand the autonomous communities with a better average collection period were Basque country with 53 days, Cantabria 83 days and Catalonia with 93 days.

Given that the turnover of the hospital sector private administrations was 1570 million euros in the year 2010 is estimated the debt at 31 December had the autonomous communities with private hospitals amounted to 688 million euros.

The employers regretted the serious non-compliance taking the greater part of the autonomous communities and urges Governments to take appropriate measures to resolve such a situation that this delay in payment by the Administration is causing serious tensions of Treasury to hospitals which puts at risk the economic viability of certain health centres.

The National Federation of private clinics is the patron of the hospital sector from the year 1977 and encompasses most of hospitals deprived of Spanish territory.

Andalusia 129 days
Aragón –
Asturias 105 days
Baleares 116 days
Canary 101 days
Cantabria 83 days
La Mancha 263 days
Castilla León 227 days
Catalonia 93 days
Extremadura 292 days
Galicia 109 days
271 days Madrid
Murcia 135 days
Navarra –
PaíBasque s 53 days
Rioja 163 days
Valencia 267 days

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Surah Al-Rehman – The Ultimate Free Remedy for Incurable Diseases

(By Listening Only- 20 Minutes Only)

Kindly download the Surah “AL-REHMAN” (recited by Qari Abdul Basit without translation) from here.


Treatment Plan

Just Listen to it three times a day (morning, afternoon, evening) for seven consecutive days using following procedure:-


    Before listening:

  • Close your eyes
  • Feel your self in front of ALLAH Almighty/ God
  • Then listen to it with greater concentration and closed eyes

    When the recitation/ AUDIO is finished:

  • Open your eyes and take half glass of water
  • Close your eyes again and say “ALLAH” three times in your heart with deep affection/ love
  • Then drink the water with closed eyes in three sips

Surah Al-Rehman – The Ultimate Free Remedy for Incurable Diseases

(By Listening Only- 20 Minutes Only)

Kindly download the Surah “AL-REHMAN” (recited by Qari Abdul Basit without translation) from here.


Treatment Plan

Just Listen to it three times a day (morning, afternoon, evening) for seven consecutive days using following procedure:-


    Before listening:

  • Close your eyes
  • Feel your self in front of ALLAH Almighty/ God
  • Then listen to it with greater concentration and closed eyes

    When the recitation/ AUDIO is finished:

  • Open your eyes and take half glass of water
  • Close your eyes again and say “ALLAH” three times in your heart with deep affection/ love
  • Then drink the water with closed eyes in three sips