Identified an antioncogén within an oncogene
[if gte mso 9] > < xml > normal 0 21 false false false MicrosoftInternetExplorer4 <!-[if gte mso 9] > < w:LatentStyles DefLockedState = “false” LatentStyleCount = “156” > <!-[if gte mso 10] > identified aantioncogén within an oncogene a studyled by Manel Esteller has discovered the existence of a moleculeanti-tumor originated within an oncogene Barcelona, June2012- A point in common in all human tumors is that they produce oneactivation of oncogenes, genes that cause cancer, and cause a lossthe role of protective genes, called antioncogenes or genessuppressors tumor. Normally both categories of genes, procancerosos andanti-cancer, are found in regions of our chromosomes. a studycoordinated by Manel Esteller, director of Epigenetics and biology programthe Institute of biomedical research of Bellvitge (IDIBELL) cancer,Professor of genetics of the University of Barcelona and ICREA researcher, hasdiscovered the existence of an antitumor molecule that originates inside ofan oncogene. The finding is published this week in the scientific journal NatureStructural & Molecular Biology. example of three tumors of colon(left image) whose growth was inhibited (right image) by themolecule of RNA (ribonucleic acid) identified which serves as antioncogén. the antioncogénidentified is a ribonucleic acid long not coding (lncRNA), i.e.,a molecule does not produce protein itself that is responsible for regulatingthe expression of other proteins. In particular, the identified molecule ismanufactured within a gene that causes cancer (SMYD3) so its role inhealthy cells is to inhibit...
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