Act on two inflammatory mediators, new strategy to combat hypertension.
Act on two inflammatory mediators, new strategy to combat high blood pressure. Spain, January 2012.- arterial hypertension is a risk factor for cardiovascular disease that affects approximately one-third of adults in Western societies. Cardiovascular disease is the leading cause of death in developed countries. Radical excess free oxygen and products of the cyclooxygenase-2 act in concert to induce vascular alterations in cardiovascular diseases such as hypertension. This relationship may represent a new route relevant to understanding the role of inflammation in these diseases. This is the finding of collaborative work developed by two research groups of the network of Cardiovascular Research (RECAVA), coordinated by Dr. Mercedes Salaices of the Autonomous University of Madrid and University Hospital Research Institute peace and coordinated by Dr. Juan Miguel Redondo from the Centre national cardiovascular research (CNIC) and which will be published in the next issue of the journal Antioxidants and Redox Signalling January. Investigadores de RECAVA (de izquierda a derecha): Angela Martín, Priscilla Batista, Ana Briones (atrás), Marisol Avendaño (delante), Sonia Martínez-Revelles (atrás), Andrea Aguado (atrás), Rosa Aras-López (delante), Mercedes Salaices (delante), Mª Jesús Alonso (atrás), Roberto Palacios (atrás), Olha Zhenyukh (delante), Laura García-Redongo (atrás)Despega Ronacher (front). Both oxidative stress (imbalance between the production of reactive oxygen species and the ability to detoxificarlas quickly) as produced by the inflammatory enzyme cyclooxygenase-2 prostanoids (derivatives of fatty acids), are involved in the pathogenesis of...
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