A breakthrough toward a vaccine against HIV, cause of Aids, happens in research with the participation of the Faculty of medicine University of São Paulo (FMUSP).

Advance

researchers have created a vaccine that works in target cells of the immune response to HIV and in most parts of the virus, which has similar characteristics to highly protective vaccines. With animal models, tests conducted at the Institute for Research in Immunology (iii-INCT), based at the FMUSP, are underway. The goal is that by the end of the year it is possible to verify whether the vaccine is protective effect, in which case could begin to be tested in humans.

professor Edécio Cunha Neto, who coordinates the research, says that there is still no effective vaccine against HIV that can be used on a large scale. The study sought to identify the gaps of vaccines already tested and what features would be desirable for a more effective

immunization.

the tests shall be carried out in Rhesus monkeys, which are infected with SIV, a virus that originated the HIV, and modified in mice with immune system similar to the

of human beings.